Eretz Yisrael Time

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Thursday, February 17, 2011
The headline for this post is a bit misleading, but potentially true none the less.

Scientists have been studying villagers of a town in Ecuador. Many of the residents have a genetic mutation that results in dwarfism.

But the mutation that causes their short stature also prevents them from getting cancer or diabetes. They apparently don't produce enough of a hormone called IGF-1 and their cells have a defective growth hormone receptor.

In laboratory experiments on mice, this defect results in extended lifespans.

Studying these villagers has helped pharmaceutical companies produce a drug (called Pegvisomant or Somavert) for helping treat a disease called acromegaly - and it might also extend lifespan.

And the Jewish connection?

Apparently these villagers are descendants of Sephardi Conversos from Portugal and Spain!
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